Proden PlaqueOffTM has been clinically proven to reduce and help prevent plaque and tartar. It is estimated 85% of dogs and 70% of cats over 3 years show signs of gum disease, the major cause of tooth loss. Gum disease is caused by the accumulation of plaque bacteria and is converted to calculus by the minerals naturally occuring in saliva. If gum disease is left untreated, it can lead to bad breath, pain, tooth loss and other health problems. By using Proden PlaqueOffTM, owners of dogs and cats can take a simple and effective step towards the animal's oral health. INGREDIENTS AND DOSAGE Suggested dose: Proden PlaqueOffTM should be added to dry or wet food on a daily basis. Each bottle contains a serving spoon to measure out the proper amount. Size Daily Dosage Average Supply for 1 Animal 60 gram Bottle Small dogs up to 25lbs. & cats 1/2 scoop 1 year Medium dogs 25-50lbs. 1 scoop 6 months Large and giant dogs 50+lbs. 2 scoops 3 months Ingredients: Natural plant marine algae D1070, minerals and trace minerals 22%, fibre 6%, proteins with all amino acids 6%, Omega-3 fatty acids 2%. Free of artificial coloring, preservatives, gluten, salt and sugar. Storage: Store at room temperature and keep out of the reach of children.